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VanPraagh R, Litovsky S
In the Wistar strain this was associated with an increase in DNA adduct levels; no such increase was observed in the F344 strain
At the time that the work was conducted, these included Wnt potentiation osteoporosis model, Insulin and GLP 1 secretion diabetes models, KRAS Wnt synthetic lethality, and Angiogenesis cancer models
It blocks the effects of estrogen, the female hormone that promotes tumor growth in HER breast cancers